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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
27.88
Human Site:
T349
Identified Species:
40.89
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
T349
L
V
D
S
R
E
A
T
S
V
P
H
I
Y
A
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
P319
L
W
A
I
G
R
V
P
D
T
R
S
L
N
L
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
T349
L
V
D
S
R
E
G
T
S
V
P
H
I
Y
A
Dog
Lupus familis
XP_850181
509
55065
T336
L
V
N
A
Q
E
A
T
S
I
P
H
I
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
T349
I
V
D
A
Q
E
A
T
S
V
P
H
I
Y
A
Rat
Rattus norvegicus
Q9Z0J5
526
56406
T351
I
V
D
A
Q
E
A
T
S
V
P
H
I
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
T343
I
V
D
A
S
E
A
T
S
V
P
H
I
Y
A
Frog
Xenopus laevis
NP_001080052
504
54666
T329
I
V
D
A
S
E
A
T
S
V
P
H
I
Y
A
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
E424
G
K
V
P
V
N
D
E
E
Q
T
N
V
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
V423
D
S
Q
E
A
T
N
V
A
N
I
Y
A
V
G
Honey Bee
Apis mellifera
NP_001171496
537
59227
V364
A
I
D
E
Q
T
N
V
P
N
V
Y
A
V
G
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
V482
E
R
A
K
S
K
K
V
L
G
R
R
E
Q
S
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
P320
S
N
E
Q
S
S
V
P
H
I
H
A
I
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
R327
V
K
V
D
E
Y
S
R
T
N
I
P
S
I
W
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
K309
G
S
E
N
V
G
I
K
L
N
S
H
D
Q
I
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
S308
V
D
E
Y
Q
N
T
S
T
E
N
I
Y
A
V
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
6.6
93.3
73.3
N.A.
80
80
N.A.
N.A.
80
80
0
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
13.3
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
13.3
N.A.
13.3
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
32
7
0
38
0
7
0
0
7
13
7
44
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
44
7
0
0
7
0
7
0
0
0
7
0
7
% D
% Glu:
7
0
19
13
7
44
0
7
7
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
7
7
7
0
0
7
0
0
0
7
13
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
50
0
0
7
% H
% Ile:
25
7
0
7
0
0
7
0
0
13
13
7
50
7
7
% I
% Lys:
0
13
0
7
0
7
7
7
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
0
0
0
13
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
7
0
13
13
0
0
25
7
7
0
7
0
% N
% Pro:
0
0
0
7
0
0
0
13
7
0
44
7
0
7
0
% P
% Gln:
0
0
7
7
32
0
0
0
0
7
0
0
0
13
0
% Q
% Arg:
0
7
0
0
13
7
0
7
0
0
13
7
0
0
0
% R
% Ser:
7
13
0
13
25
7
7
7
44
0
7
7
7
0
7
% S
% Thr:
0
0
0
0
0
13
7
44
13
7
7
0
0
0
0
% T
% Val:
13
44
13
0
13
0
13
19
0
38
7
0
7
13
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
7
0
0
0
0
0
13
7
44
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _